The main part of cooling and freezing is within food applications. MPG or 1,2-MonoPropylene Glycol is perhaps the most commonly used heat transfer fluid in those applications. Already at below -20°C the viscosity of MPG is very high and the energy demand increase significantly. Already @ -30°C, the viscosity gets too high for practical use in centrifugal pumps. A thumb rule is that at kinematic viscosity above 300 cSt, centrifugal pumps cannot be used. Other types of pumps are very expensive and inefficient. The calculations (Reynolds number, pressure drop and heat transfer coefficient) are made for circular tubes.